Sangre de drago

Croton lechleri L.

Bibliografia

  • Aquino, R, De Feo, V, De Simone, F, De Tommasi, N, Pizza, C (1996) Flora officinale dell’america latina. Contributo allo studio della flora andina. Gutemberg Edizioni, Salerno.
  • Blumberg PM. (1988) “Protein kinase C as the receptor for the phorbol ester tumor promoters: Sixth Rhoads memorial award lecture”. Cancer Res; 48: 1-8.
  • Chen ZP, Cai Y, Phillipson JD. (1994) “Studies on the anti-tumour, anti-bacterial, and wound-healing properties of dragon's blood.” Planta Med.; 60(6): 541-5
  • Desmarchelier C, Wiiting Schaus F, Coussio J and Cicca G (1997): Effects of Sangre de Drago from Croton lechlerii on the production of active oxygen radicals. Journ of Ethnopharmacol., 58, 103-108.
  • DiCesare D, Dupont HL, Mathewson JJ, Ericsson CD, Ashley D, Matinez-sandoval FG, Pennington JE and Porter SB (1998): A Double-Blind, Randomized, Placebo-Controled Study of SP-303 in the Symptomatic Treatment of Acute Diarrhea Among Travelers to Mexico and Jamaica. Infect Dis. Society of America. 36th Ann. Meet, Denver.
  • Fischer H, Machen TE, Widdicombe JH, Carlson TJ, King SR, Chow JW, Illek B. (2004) “A novel extract SB-300 from the stem bark latex of Croton lechleri inhibits CFTR-mediated chloride secretion in human colonic epithelial cells.” J Ethnopharmacol.; 93(2-3): 351-7.
  • Gabriel SE, Davenport SE, Steagall RJ, Vimal V, Carlson T, Rozhon EJ. (1999) “A novel plant-derived inhibitor of cAMP-mediated fluid and chloride secretion.” Am J Physiol; 276: G58-63.
  • Holodniy M, Koch J, Mistal M, Maimares, Schmidt JM, Khandwala A, Pennington JE and Porter SB (1999): A Double Blind, Randomized, Placebo-Controlled Phase II to Assess the Safety and Efficacy of Orally Administred SP-303 for teh Symptomatic Treatment of Diarrhea in Patients with AIDS: Am. J. of Gatroenter., 94, 3267-3273.
  • Meza EN (Ed): Desarrollando nuestra diversidad biocultural. ""Sangre de Drago"" y el reto de su producion sustentable en el Perù. Universidad Nacional Mayor de San Marcos, Lima.
  • Miller MJS, Vergnolle N, McKnight W, Musah RA, Davison CA, Trentacosti AM, Thompson JH, Sandoval M, Wallace JL. (2001) “Inhibition of neurogenic inflammation by the Amazonian herbal medicine Sangre de Drago.” J Invest Dermatol; 117: 725-730
  • Miller MJS, Vergnolle N, Wallace JL, Mac Naughton WK, Upender M, Davison C, Zhang XJ, Sandoval M (2000): Sangre de Drago is a potent and unique inhibitor of neurogenic inflammation and promotes healing in experimental necrotizing enterocolitis. PAAS/AAP, Ab. 979.
  • Mongelli E, Desmarchelier C, GIUlietti A, Coussio J and Ciccia G (1995): Bioactivity of certain latexes used by Ese'ejas. Journ. of Ethnopharmacol., 47, 159-163.
  • Orozco-Topete R, Sierra-Madero J, Cano-Dominguez C, Kerschenovich J, Ortiz-Pedroza G, Vazquez-Valls E, Garcia-Cosio C, Soria-Cordoba A, Armendariz AM, Terran-Toledo X, Romo-Garcia J, Fernandez H and Rozhon EJ (1997): Safety and Efficacy of Virend for topical traetment of genital and anal herpes simplex lesions in patients with AIDS. Antiviral Res., 35, 91-103.
  • Perdue GP, Blomster RN, Blake DA, Farnsworth NR. (1979) "South American plants II: taspine isolation and anti-inflammatory activity" J Pharm Sci.; 68(1): 124-6.
  • Persinos Perdue G, Blomster R, Blake DA, Farnsworth NR (1979): South American Plants II: Taspine Isolation and Anti-Inflammatory Activity. Journ. of Pharmaceuical Sciences, 68, 124-125
  • Pieters L. (1998) “La “Sangre de drago” una droga tradicional de Sudamerica. Constituyentes biologicamente activos”. Ediciones Abya-Yala, Quito-Ecuador,.
  • Pieters L, De Bruyne T, Claeys M, Vlietinck A, Calomme M, Vanden Berghe D. (1993) “Isolation of a dihydrobenzofuran lignan from South American dragon's blood (Croton spp.) as an inhibitor of cell proliferation.” J Nat Prod.; 56(6): 899-906
  • Pieters L, De Bruyne T, Mei G, Lemiere G, Vanden Berghe and Vlientinck J (1992): In Vitro and In Vivo Biological Activity of South American Dragon's Blood and its Costituents. Planta Medica 58, Suppl 1, A582-A583
  • Pieters L, De Bruyne T, Van Poel B, Vingerhoets R, Tottè J, Vanden Berghe D and Vlientick A (1995): In vivo wound healing activity of Dragon's Blood (Croton spp.), a traditional South American drug and its costituents. Phytomedicine, 2(1), 17-22.
  • Porras-Reyes BH, Lewis WH, Roman J, Simchowitz L and Mustoe TA (1993): Enhancement of wound healing by the alkaloid taspine defining mechanism of action. Journ. of Experimental Biol and Medicine, 203. 18-25.
  • Risco E, Ghia F, Vila R, Iglesias J, Alvarez E, Canigueral S. (2003) “Immunomodulatory activity and chemical characterisation of Sangre de Drago (dragon's blood) from Croton lechleri.” Planta Med.; 69(9): 785-94);
  • Rossi D, Bruni R, Bianchi N, Chiarabelli C, Gambari R, Medici A, Lista A, Paganetto G. (2003) “Evaluation of the mutagenic, antimutagenic and antiproliferative potential of Croton lechleri (Müell. Arg.) latex.” Phytomedicine.; 10(2-3): 139-44
  • Safrin S, McKinley G, Mc Keough, Robinson D, Spruence Sl (1994): Treatment of Acyclovir-unresponsive cutaneous Herpes simplex virus infection with topically applied SP-303. Antiviral Res., 25, 185-192.
  • Stevens, P.F. (2001 onwards). Angiosperm Phylogeny Website. Version 5, May 2004 [and more or less continuously updated since]. http://www.mobot.org/MOBOT/research/APweb/.
  • Vaisberg AJ, Milla M, Planas MdC, Cordova JL, de Agusti ER, Ferreyra R, Mustiga MdC, Carlin L and Hammond GB (1988): Taspine is the cicatrizant principle in Sangre de Drago Extracted from Croton lechler. Planta Medica, 55, 140-142.
  • Vlietinck AJ, Dommisse RA, eds (1985) Advances in medicinal plant research. Stuttgart: Wiss. Verlag

Glossario